Cardiovascular disease

2020

Systemic Mesenchymal Stem Cell-Derived Exosomes Reduce Myocardial Infarct Size: Characterization With MRI in a Porcine Model. Frontiers in Cardiovascular Medicine, 7, Article 601990. Charles, C. J., Li, R. R., Yeung, T., Mazlan, S. M. I., Lai, R. C., de Kleijn, D. P. V., Lim, S. K., & Richards, A. M. (2020).  Link

2013

Mesenchymal stem cell exosome ameliorates reperfusion injury through proteomic complementation. Regenerative medicine8(2), 197–209.Lai, R. C., Yeo, R. W., Tan, K. H., & Lim, S. K. (2013).   Link

Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury. Stem cell research10(3), 301–312. Arslan, F., Lai, R. C., Smeets, M. B., Akeroyd, L., Choo, A., Aguor, E. N., Timmers, L., van Rijen, H. V., Doevendans, P. A., Pasterkamp, G., Lim, S. K., & de Kleijn, D. P. (2013). Link

2011

Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction. Stem cell research6(3), 206–214. Timmers, L., Lim, S. K., Hoefer, I. E., Arslan, F., Lai, R. C., van Oorschot, A. A., Goumans, M. J., Strijder, C., Sze, S. K., Choo, A., Piek, J. J., Doevendans, P. A., Pasterkamp, G., & de Kleijn, D. P. (2011).  Link

Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease. Regenerative Medicine, 6(4), 481-492. Lai, R. C., Chen, T. S., & Lim, S. K. (2011).  Link

2010

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury. Stem cell research4(3), 214–222. Lai, R. C., Arslan, F., Lee, M. M., Sze, N. S., Choo, A., Chen, T. S., Salto-Tellez, M., Timmers, L., Lee, C. N., El Oakley, R. M., Pasterkamp, G., de Kleijn, D. P., & Lim, S. K. (2010). Link

2008

Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium. Stem cell research1(2), 129–137. Timmers, L., Lim, S. K., Arslan, F., Armstrong, J. S., Hoefer, I. E., Doevendans, P. A., Piek, J. J., El Oakley, R. M., Choo, A., Lee, C. N., Pasterkamp, G., & de Kleijn, D. P. (2007).  Link

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