Tan SS, Yin Y, Lee T, Lai RC, Yeo RW, Zhang B, Choo A, Lim SK. Therapeutic MSC exosomes are derived from lipid raft microdomains in the plasma membrane. J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22614. eCollection 2013. PubMed PMID: 24371518; PubMed Central PMCID: PMC3873122. Link

Wang JW, Gijsberts CM, Seneviratna A, de Hoog VC, Vrijenhoek JE, Schoneveld AH, Chan MY, Lam CS, Richards AM, Lee CN, Mosterd A, Sze SK, Timmers L, Lim SK, Pasterkamp G, de Kleijn DP. Plasma extracellular vesicle protein content for diagnosis and prognosis of global cardiovascular disease. Neth Heart J. 2013 Oct;21(10):467-71. doi: 10.1007/s12471-013-0462-3. PubMed PMID: 23975618; PubMed Central PMCID: PMC3776081. Link

Yeo WYR, Lai RC, Tan KH and Lim SK. Exosome: A Novel and Safer Therapeutic Refinement of Mesenchymal Stem Cell. Exosomes Microvesicles 2013 1:7. doi: 10.5772/57460. Link

Chen T, Yeo R, Arslan F, Yin Y, Tan SS, Choo A, Padmanabhand J, Lee CN, de Kleijn DPV, Tan KH and Lim SK. Efficiency of Exosome Production Correlates Inversely with the Developmental Maturity of MSC Donor. 2013 J Stem Cell Res Ther 3, 2. Link

Ren Y, Hao P, Dutta B, Cheow ES, Sim KH, Gan CS, Lim SK, Sze SK. Hypoxia modulates A431 cellular pathways association to tumor radioresistance and enhanced migration revealed by comprehensive proteomic and functional studies. Mol Cell Proteomics. 2013 Feb;12(2):485-98. doi: 10.1074/mcp.M112.018325. Epub 2012 Nov 30. PubMed PMID: 23204318; PubMed Central PMCID: PMC3567868. Link

Chen TS, Lim SK. Measurement of precursor miRNA in exosomes from human ESC-derived mesenchymal stem cells. Methods Mol Biol. 2013;1024:69-86. doi: 10.1007/978-1-62703-453-1_6. PubMed PMID: 23719943. Link

Lai RC, Yeo RW, Tan KH, Lim SK. Exosomes for drug delivery - a novel application for the mesenchymal stem cell. Biotechnol Adv. 2013 Sep-Oct;31(5):543-51. doi: 10.1016/j.biotechadv.2012.08.008. Epub 2012 Aug 25. Review. PubMed PMID: 22959595. Link

Lai RC, Yeo RW, Tan KH, Lim SK. Mesenchymal stem cell exosome ameliorates reperfusion injury through proteomic complementation. Regen Med. 2013 Mar;8(2):197-209. doi: 10.2217/rme.13.4. Review. PubMed PMID: 23477399. Link

Yeo RW, Lai RC, Zhang B, Tan SS, Yin Y, Teh BJ, Lim SK. Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery. Adv Drug Deliv Rev. 2013 Mar;65(3):336-41. doi: 10.1016/j.addr.2012.07.001. Epub 2012 Jul 7. Review. PubMed PMID: 22780955 Link

Kanhai DA, Visseren FL, van der Graaf Y, Schoneveld AH, Catanzariti LM, Timmers L, Kappelle LJ, Uiterwaal CS, Lim SK, Sze SK, Pasterkamp G, de Kleijn DP; SMART Study Group. Microvesicle protein levels are associated with increased risk for future vascular events and mortality in patients with clinically manifest vascular disease. Int J Cardiol. 2013 Oct 3;168(3):2358-63. doi: 10.1016/j.ijcard.2013.01.231. Epub 2013 Feb 26. PubMed PMID: 23484740. Link

Lai R, Yeo R, Tan S, Zhang B, Yin Y, Sze S, Choo A, and Lim S. Mesenchymal Stem Cell Exosomes: The Future MSC-Based Therapy? 2013. In Mesenchymal Stem Cell Therapy, L.G.V. Chase, Mohan C. , ed. (Humana Press), pp. 39-62. ISBN 978-1-62703-200-1.

Arslan F, Smeets MB, Buttari B, Profumo E, Riganò R, Akeroyd L, Kara E, Timmers L, Sluijter JP, van Middelaar B, den Ouden K, Pasterkamp G, Lim SK, de Kleijn DP. Lack of haptoglobin results in unbalanced VEGFα/angiopoietin-1 expression, intramural hemorrhage and impaired wound healing after myocardial infarction. J Mol Cell Cardiol. 2013 Mar;56:116-28. doi: 10.1016/j.yjmcc.2012.12.012. Epub 2012 Dec 26. PubMed PMID: 23274064. Link

Arslan F, Lai RC, Smeets MB, Akeroyd L, Choo A, Aguor EN, Timmers L, van Rijen HV, Doevendans PA, Pasterkamp G, Lim SK, de Kleijn DP. Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury. Stem Cell Res. 2013 May;10(3):301-12. doi: 10.1016/j.scr.2013.01.002. Epub 2013 Jan 14. PubMed PMID: 23399448. Link


"Living well with stem cell exosomes"