Business Concept

Chronic non-communicable diseases constitute the most dominant disease group in the world.  In an increasing affluent world with improved sanitation and healthcare, aging and unhealthy life style are the major causes of illness and diseases. While prevention is still the best policy in managing this health challenges, it is not always possible. Many of these diseases do not have cures but only support therapies to manage pain and prevent further deterioration. At present, the most promising therapeutic option that could offer a more permanent resolution for these diseases is adult stem cell regenerative medicine. 

New Paradigm in Stem Cell Regenerative Medicine

Scientists recently discovered that in regenerative medicine, adult stem cells work by secreting small vesicles called exosomes to be taken by other cells. Exosomes are~100 nm lipid membrane vesicles  carrying proteins and nucleic acids of the secreting cells. Therefore, stem cell exosomes are rich in stem cell proteins and nucleic acids. They are easily taken up by diseased or injured cells. This enables stem cell-like proteins and nucleic acids to be transferred to diseased or injured cells to facilitate repair and regeneration. A*STAR scientists were the first to discover the therapeutic potency of adult stem cell exosomes. Since then, independent investigations around the world confirm that adult stem cell exosomes are as efficacious as stem cells in regenerative medicine.

Stem Cell Exosome: Transforming Stem Cell Regenerative Medicine

The use of living cells is a major hindrance to the development of conventional stem cell regenerative medicine. Living cell-based medicine require stringent manufacturing, storage, transport and administration to ensure that cells remain viable, potent and non-mutated. Hence, replacing living stem cells with their exosomes obviates many of these challenges. In addition, non-living exosomes cannot formed tumors. Their potency can be preserved by freezing without potentially dangerous chemicals. They are not immunogenic and can be used universally for all patients. 

One Drug Many Diseases



"Living well with stem cell exosomes"