Osteoarthritis (OA)

2021

Mesenchymal stromal cell-derived small extracellular vesicles modulate macrophage polarization and enhance angio-osteogenesis to promote bone healing. Genes & diseases9(4), 841–844. Chuah, S. J., Yong, C. W., Teo, K. Y. W., Chew, J. R. J., Cheow, Y. A., Zhang, S., Wong, R. C. W., Lim, A. A. T., Lim, S. K., & Toh, W. S. (2021). Link

2020

Intra-Articular Injections of Mesenchymal Stem Cell Exosomes and Hyaluronic Acid Improve Structural and Mechanical Properties of Repaired Cartilage in a Rabbit Model. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association36(8), 2215–2228.e2. Wong, K. L., Zhang, S., Wang, M., Ren, X., Afizah, H., Lai, R. C., Lim, S. K., Lee, E. H., Hui, J. H. P., & Toh, W. S. (2020).  Link

2019

Mesenchymal stem cell exosomes enhance periodontal ligament cell functions and promote periodontal regeneration. Acta biomaterialia89, 252–264. Chew, J. R. J., Chuah, S. J., Teo, K. Y. W., Zhang, S., Lai, R. C., Fu, J. H., Lim, L. P., Lim, S. K., & Toh, W. S. (2019).  Link

MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis. Biomaterials200, 35–47. Zhang, S., Teo, K. Y. W., Chuah, S. J., Lai, R. C., Lim, S. K., & Toh, W. S. (2019). Link

2017

MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity. Biomaterials156, 16–27. Zhang, S., Chuah, S. J., Lai, R. C., Hui, J. H. P., Lim, S. K., & Toh, W. S. (2018). Link

2016

MSC exosome as a cell-free MSC therapy for cartilage regeneration: Implications for osteoarthritis treatment. Seminars in cell & developmental biology67, 56–64.Toh, W. S., Lai, R. C., Hui, J. H. P., & Lim, S. K. (2017).   Link

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